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Modifying the gut microbiome and personalised anti-tumour vaccines

Written by | 11 Nov 2019

Tumours use a variety of mechanisms to escape the host immune system and overcoming these to increase response rates and improve quality of life are key goals. Manipulation… read more.

Targetable mutations key learnings

Written by | 11 Nov 2019

Targeted treatments for mutation-driven non-small cell lung cancer have advanced considerably but many questions remain about how to use these drugs to the best advantage and how to… read more.

Optimal delivery of immunotherapy in advanced NSCLC

Written by | 11 Nov 2019

Immunotherapy has been hailed as a “game changer” in the treatment of lung cancer. As experience and understanding grows, optimal ways of delivering this type of treatment are… read more.

Immunotherapy – where are we now?

Written by | 11 Nov 2019

Immunotherapy now has an established place in treatment of non-small cell lung cancer but many questions remain such as the role of tumour mutational burden as a biomarker… read more.

Transplantation, Consolidation and Maintenance

Written by | 8 May 2019

  Autologous stem cell transplantation (ASCT) remains the standard of care option for those patients with newly-diagnosed multiple myeloma (MM) who are eligible for and able to tolerate… read more.

ASCO 2018: Choices for front-line NSCLC

Written by | 20 Aug 2018

With permutations of potential front-line treatments for non-small cell lung cancer (NSCLC) seemingly endless, one thing seems certain…

EHA 2018: Immunotherapy in MM: why, when and how?

Written by | 24 Jun 2018

The pathophysiology of MM is characterised by a state of profound immunosuppression through multiple mechanisms which provides a strong rationale for immunotherapeutic approaches including antibodies, immunomodulators, vaccines and… read more.

EHA 2018: Preferred treatment combinations and sequencing in transplant eligible and elderly MM patients

Written by | 24 Jun 2018

The growing number of novel treatments for multiple myeloma (MM) means that more patients can achieve the therapeutic goal of a deep and prolonged first remission – in… read more.

BSH 2017: Management of Asymptomatic Follicular Lymphoma

Written by | 24 Apr 2017

The old mantra is that advanced follicular lymphoma (FL) cannot be cured and treatment does not influence survival but this is no longer the case – follicular lymphoma… read more.

ESMO 2016: True burden of head and neck cancer underestimated (France)

Written by | 16 Jan 2017

by Gary Finnegan A nationwide study of head and neck cancers in France has revealed that the true burden of the disease is underestimated by at least one-third,… read more.

ESMO 2014 Report: FOLFIRI plus cetuximab in patients with liver-limited or non-liverlimited RAS wild-type metastatic disease

Written by | 24 Nov 2014

by Esther Drain:  A sub-group analysis of the CRYSTAL study.  In the CRYSTAL study, adding cetuximab (cet) to first-line chemotherapy (CT) improved clinical outcome in patients (pts) with RAS… read more.

ESMO 2014 Report: Special symposium on ‘Advances in precision medicine of metastatic colorectal cancer’

Written by | 21 Nov 2014

by Denys Wheatley: There is some irony in the title of this symposium because medicine should always be as precise as it can, and advances are expected that… read more.

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