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Bladder-sparing strategies in the management of muscle-invasive bladder cancer

Written by | 19 Sep 2022

For many years surgery has been regarded as the gold standard for MIBC but now comparative trials, epidemiological findings and a meta-analysis of trials all show that outcomes… read more.

Current trials with intravesical treatment in high-risk BCG-naïve NMIBC

Written by | 19 Sep 2022

Intravesical therapy with chemotherapy or BCG is the recommended adjuvant treatment after TURBT to minimise the risk of recurrence. BCG shortages continue and BCG is not suitable for… read more.

En bloc resection vs TURBT for NMIBC

Written by | 19 Sep 2022

The traditional surgical technique for TURBT involves piecemeal removal of the tumour whereas en bloc resection (ERBT) removes the whole tumour in one piece. Professor Jørgen Bjerggaard Jensen (Aarhus, Denmark)… read more.

Immunotherapy: Adjuvant immune checkpoint inhibitors for everybody?

Written by | 19 Sep 2022

The introduction of immunotherapy with immune checkpoint inhibitors has improved outcomes in trials. In this video Professor Morgan Roupret explains the current situation regarding immunotherapy and bladder cancer: This session… read more.

Lynch syndrome – what urologists need to know

Written by | 19 Sep 2022

Lynch syndrome, an inherited cancer syndrome, has been prominently associated with colorectal cancer but other organs, including the urinary tract can also be affected. As a hereditary condition,… read more.

Older adults with advanced bladder cancer prioritize honest information about what to expect

Written by | 11 Jul 2022

The median age for receiving a bladder cancer diagnosis is 73, and a significant number of those living with the disease are in their 70s and 80s. A longstanding stereotype… read more.

CHMP recommends Opdivo for the adjuvant treatment of adults with muscle-invasive urothelial carcinoma – BMS

Written by | 6 Jul 2022

Bristol Myers Squibb announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of Opdivo (nivolumab) for the… read more.

Robotic surgery is safer and improves patient recovery time

Written by | 19 May 2022

Robot-assisted surgery used to perform bladder cancer removal and reconstruction enables patients to recover far more quickly and spend significantly (20 per cent) less time in hospital, concludes… read more.

Potential therapy may boost chemoimmunotherapy response in bladder cancer

Written by | 30 Mar 2022

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancerinvestigators. The… read more.

FDA grants regular approval and expands indication for Padcev for patients with locally advanced or metastatic urothelial cancer

Written by | 16 Jul 2021

Seagen Inc. and Astellas Pharma Inc. announced the FDA granted Padcev (enfortumab vedotin-ejfv) regular approval in the U.S., in addition to approving a new indication for adult patients… read more.

FDA oncological drugs advisory committee votes in support of Tecentriq in bladder cancer – Genentech/Roche

Written by | 4 May 2021

Genentech/Roche announced the FDA Oncologic Drugs Advisory Committee voted 10 to 1 in favor of maintaining accelerated approval of Tecentriq (atezolizumab) for the treatment of adults with locally… read more.

FDA grants accelerated approval to Trodelvy for the treatment of metastatic urothelial cancer – Gilead Sciences

Written by | 22 Apr 2021

Gilead Sciences, Inc. announced that the FDA has granted accelerated approval of Trodelvy (sacituzumab govitecan-hziy) for use in adult patients with locally advanced or metastatic urothelial cancer (UC)… read more.

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