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ASCO 2015 Report: Pembrolizumab shows “remarkable” efficacy in head and neck cancer

Written by | 8 Jun 2015

by Bruce Sylvester: Pembrolizumab (Keytruda®), an anti-PD-1 antibody immunotherapy has shown efficacy in one fourth of patients with recurrent or metastatic head and neck cancer, researchers reported on… read more.

ASCO Report 2015: Immunotherapy nivolumab improves survival in squamous-non-small cell lung cancer

Written by | 4 Jun 2015

by Bruce Sylvester: In a Phase III trial comparing standard docetaxel chemotherapy with immunotherapy nivolumab, researchers reported that subjects with squamous-non-small cell lung cancer treated with nivolumab lived… read more.

Why almost half of patients opt out of comprehensive cancer testing

Written by | 7 May 2015

Results highlight importance of pre-test counselling for at-risk patient populations.  Some at-risk patients opted out of comprehensive cancer gene screening when presented with the opportunity to be tested… read more.

Dual therapy for metastatic melanoma results in longer overall survival

Written by | 23 Jan 2015

by Bruce Sylvester: Patients with metastatic melanoma treated with dual sargramostim/ipilimumab rather than ipilimumab alone have achieved longer overall survival and lower toxicity, but no difference in progression-free… read more.

ASH 2014: T-cell lymphomas: a challenge for clinicians

Written by | 19 Dec 2014

by Thomas R. Collins: Treating patients with T-cell lymphomas is fraught with challenges, requiring new approaches and sharper diagnosis, said Timothy Illidge, MD, PhD, Professor of Targeted Therapy… read more.

ESMO 2014 Report: FOLFIRI plus cetuximab in patients with liver-limited or non-liverlimited RAS wild-type metastatic disease

Written by | 24 Nov 2014

by Esther Drain:  A sub-group analysis of the CRYSTAL study.  In the CRYSTAL study, adding cetuximab (cet) to first-line chemotherapy (CT) improved clinical outcome in patients (pts) with RAS… read more.

ESMO 2014 Report: Adolescent and young adult cancer patients

Written by | 20 Nov 2014

Engagement of patients and understanding of early death in this group by Denys Wheatley. (1) When and why do teenage and young adult oncology patients die early in… read more.

ESMO 2014 Report: How to integrate genome sequencing data in oncology

Written by | 13 Nov 2014

by Denys Wheatley: Chaired by Atsushi Ohtsu and Jean-Yves Douillard, the first speaker Dr Kato (Japan) addressed the issue of the quest for different mutations in the hope… read more.

ESMO 2014 Report: Precision medicine: Panacea or false dawn?

Written by | 6 Nov 2014

Reports from the European Society for Medical Oncology 2014 Congress in Madrid by Denys Wheatley:  In his talk on Visualising the true spectrum of cancer- will we get… read more.

Bendamustne Lymphoma Case Study

Written by | 4 Nov 2014

Ger Walpole, CNS (Clinical Nurse Specialist), H.Dip Oncology Nursing, BNS(Hons), Sligo Regional Hospital, Sligo.   Dr Andrew Hodgson, MB, BS, BSc (Hons), FRCPI, FFPath, FRCPath.   Written by Karen Mas-Mollinedo… read more.

ESMO 2014 Report: Patients with Hodgkin’s lymphoma have a significantly better outcome if treated within a clinical trial

Written by | 14 Oct 2014

by Denys Wheatley: ESMO  Madrid September 2014: Session on Sunday 28 September (poster).  Dr Moccia and his group in Bellinzona (Switzerland) report on the marked improvement over 30… read more.

Metformin treatment associated with low thyroid hormone

Written by | 1 Oct 2014

by Bruce Sylvester – Researchers report that metformin therapy, a treatment for type 2 diabetes, could induce a lowering thyroid-stimulating hormone (TSH) in patients with underactive thyroids (hypothyroidism)…. read more.

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