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New approach to prostate cancer treatment increases survival for some patients

Written by | 28 Aug 2015

by Bruce Sylvester: Among patients with metastatic hormone-sensitive prostate cancer, chemotherapy with docetaxel at the start of androgen deprivation therapy (ADT) has resulted in an increased survival of… read more.

Oral contraceptive use lowers endometrial cancer risk

Written by | 26 Aug 2015

by Bruce Sylvester: Oral contraceptive use appears to provide long-term protection against endometrial cancer, researchers reported on August 4, 2015 in The Lancet Oncology.

Daily bathing of pediatric patients with antiseptic cuts bloodstream infections by 59 percent

Written by | 21 Jul 2015

Daily bathing of pediatric patients with disposable cloths containing 2 percent chlorhexidine gluconate (CHG) reduced central line-associated bloodstream infections (CLABSIs) by 59 percent and saved approximately $300,000 in… read more.

Rociletinib could become a “game changer” in treating EGFR-mutation driven lung tumors which have become treatment resistant

Written by | 6 Jul 2015

by Bruce Sylvester: Rociletinib, an investigative therapy for treatment resistant EGFR-mutation driven lung tumors, shows activity against the most common resistance mutation, and it significantly improves clinical  outcomes.

World Health Matters: Ireland: Early palliative care delivers cost savings

Written by | 1 Jul 2015

by Gary Finnegan: People with terminal cancer often require palliative care in the late stages of their lives. This branch of medicine has long been lauded for the… read more.

ASCO 2015 Report: New, less toxic, treatment emerges for difficult-to-treat breast cancer

Written by | 11 Jun 2015

by Bruce Sylvester: Investigators from the phase III PALOMA-3 trial report that treatment with the recently FDA-approved drug palbociclib more than doubled the time to cancer recurrence among… read more.

ASCO 2015 Report: Dual immunotherapy improves progression-free survival in advanced melanoma

Written by | 10 Jun 2015

by Bruce Sylvester: Treatment of advanced melanoma with a combination of  nivolumab (Opdivo™) and ipilimumab (Yervoy™) or with nivolumab alone increases progression-free survival over ipilimumab monotherapy, researchers reported… read more.

ASCO 2015 Report: In noninvasive breast cancer, anastrozole tops tamoxifen for recurrence prevention in postmenopausal women under 60

Written by | 9 Jun 2015

by Bruce Sylvester: Anastrozole is significantly more effective than tamoxifen in preventing cancer recurrence after lumpectomy and radiation therapy in postmenopausal women, age 60 or younger with DCIS… read more.

ASCO 2015 Report: Pembrolizumab shows “remarkable” efficacy in head and neck cancer

Written by | 8 Jun 2015

by Bruce Sylvester: Pembrolizumab (Keytruda®), an anti-PD-1 antibody immunotherapy has shown efficacy in one fourth of patients with recurrent or metastatic head and neck cancer, researchers reported on… read more.

ASCO Report 2015: Immunotherapy nivolumab improves survival in squamous-non-small cell lung cancer

Written by | 4 Jun 2015

by Bruce Sylvester: In a Phase III trial comparing standard docetaxel chemotherapy with immunotherapy nivolumab, researchers reported that subjects with squamous-non-small cell lung cancer treated with nivolumab lived… read more.

Why almost half of patients opt out of comprehensive cancer testing

Written by | 7 May 2015

Results highlight importance of pre-test counselling for at-risk patient populations.  Some at-risk patients opted out of comprehensive cancer gene screening when presented with the opportunity to be tested… read more.

Dual therapy for metastatic melanoma results in longer overall survival

Written by | 23 Jan 2015

by Bruce Sylvester: Patients with metastatic melanoma treated with dual sargramostim/ipilimumab rather than ipilimumab alone have achieved longer overall survival and lower toxicity, but no difference in progression-free… read more.

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