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Pfizer and BioNTech announce submission of initial data to FDA to support booster dose of COVID-19 Vaccine

Written by | 31 Aug 2021

Pfizer Inc. and BioNTech SE announced that they have submitted Phase 1 data to the FDA to support the evaluation of a third, or booster, dose of the… read more.

Ronapreve, the first monoclonal antibody treatment for COVID-19 approved for use in the UK – Regeneron + Roche

Written by | 26 Aug 2021

Following on from a thorough review of the evidence carried out by the MHRA, and recommendation by the Commission on Human Medicines (CHM), the government’s independent expert scientific… read more.

Anticoagulation therapy improves outcomes in moderately ill COVID-19 patients

Written by | 24 Aug 2021

Moderately ill patients hospitalized with COVID-19 have achieved a better rate of respiratory organ support-free days and survival if treated with therapeutic-dose anticoagulation, researchers reported on August 20,2021… read more.

Vaxzevria and mRNA COVID-19 vaccines showed similar and favourable safety profiles in a population-based cohort study of over a million people – AstraZeneca

Written by | 14 Aug 2021

In a large real-world study, data published as a pre-print on The Lancet server from over one million individuals assessed the incidence rates of blood clotting disorders of… read more.

Applying the results of the ivermectin meta-analysis

Written by | 12 Aug 2021

The results of the ivermectin meta-analysis could have important implications for health policy. Dr Edmund Fordham, one of the co-authors of the review, describes how the findings could… read more.

Critical questions on the ivermectin meta-analysis

Written by | 12 Aug 2021

The methodological approach to the ivermectin meta-analysis provides further reassurance of the robustness of the findings. Mr Andrew Bryant and Dr Edmund Fordham describe some of the critical… read more.

Putting the findings of the ivermectin meta-analysis into perspective

Written by | 12 Aug 2021

The Bryant-Lawrie meta-analysis included only randomised controlled trials (RCTs) but evidence from observational trials and real world experience sheds further light on the effectiveness of ivermectin, according to… read more.

Key findings from the ivermectin meta-analysis

Written by | 12 Aug 2021

June 2021 saw the publication of the systematic review and meta-analysis of randomised controlled trials of ivermectin for treatment and prophylaxis of covid-19 undertaken by Dr Tess Lawrie’s… read more.

Johnson & Johnson single-shot COVID-19 vaccine demonstrated a durable immune response and elicited dual mechanisms of protection against delta and other SARS-CoV-2 variants in data published in NEJM

Written by | 30 Jul 2021

Interim results from a Phase 1/IIa sub-study published in the New England Journal of Medicine (NEJM) demonstrated that both humoral (antibody) and cellular (T-cell) immune responses generated by… read more.

Lilly and Incyte provide update on supplemental NDA for baricitinib for the treatment of moderate to severe atopic dermatitis

Written by | 24 Jul 2021

Eli Lilly and Company and Incyte announced that the FDA will not meet the Prescription Drug User Fee Act (PDUFA) action date for the supplemental new drug application… read more.

Ivermectin – the unfolding story

Written by | 24 Jul 2021

IMI has been reporting on ivermectin since December 2020, keeping our readers and viewers up-to-date with research and practice developments. To mark World Ivermectin Day (24th July 2021),… read more.

Hospitals prevent deadly fungal infection during pandemic

Written by | 20 Jul 2021

As COVID-19 infections threatened to overwhelm hospitals in March 2020, infection control specialists worried not just about SARS-CoV-2 but also about other viral, bacterial and fungal diseases. C…. read more.

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