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ASCO 2014 Report: Second-line treatment data in FIRE 3 trial raises questions about clinical choices

Written by | 10 Jun 2014

by Bruce Sylvester – In the FIRE 3 trial, clinicians favored the use of second-line antibodies in patients with KRAS wild-type metastatic colorectal cancer (mCRC) with shorter first-line progression free… read more.

ASCO 2014 Report – KRAS exon 2 gene mutations appear to predict time to recurrence or disease-free survival in stage III colon cancer

Written by | 9 Jun 2014

by Bruce Sylvester – KRAS exon 2 mutations are independent predictors of time to recurrence or disease-free survival among patients with stage III distal colon cancer who are receiving… read more.

ASCO 2014 Report – Early response to chemotherapy in colorectal cancer correlated to higher prolonged survival

Written by | 6 Jun 2014

by Bruce Sylvester – Metastatic colorectal cancer patients who achieved early response to first-line chemotherapy also achieved significantly higher rates of prolonged survival, compared to patients who did… read more.

ASCO 2014 Report – Survival not significantly affected by disease site in metastatic colorectal cancer

Written by | 6 Jun 2014

by Bruce Sylvester – Survival based on primary site of disease is not significantly different among metastatic colorectal cancer patients, Australian researchers reported in a poster presentation at… read more.

Treatment outcome according to tumour RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized to FOLFIRI with/without cetuximab.

Written by | 5 Jun 2014

Adapted from Abstract 3506, which was submitted to ASCO Congress 2014 Treatment outcome according to tumour RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized… read more.

Pancreatic cancer fatalities set to rise

Written by | 23 May 2014

World Health Matters by Gary Finnegan – Italy – Death rates from pancreatic cancer are predicted to increase in men and women in 2014 and beyond, according to… read more.

Deaths from viral hepatitis surpasses HIV/AIDS

Written by | 22 May 2014

World Health Matters by Gary Finnegan – Australia – The number of deaths from viral hepatitis in Australia has surpassed the number of preventable AIDS-related deaths, according to… read more.

Green light for new cancer medicine

Written by | 21 May 2014

EMA Highlights by Gary Finnegan – At its April meeting, the EMA’s influential Committee for Medicinal Products for Human Use (CHMP) recommended that a marketing authorisation be granted… read more.

Adenoma detection tracks ongoing risk of colorectal cancer

Written by | 14 May 2014

by Thomas R. Collins – A retrospective study of over 224,000 patients who underwent over 314,000 colonoscopies indicates that pre-cancerous adenoma detection tracks the future risk of colorectal… read more.

Cbl-b, a target for drugs used to treat allergic asthma

Written by | 7 May 2014

Enzyme’s role is to ‘throw away’ protein if it overstays its welcome during immune response.  An enzyme that helps maintain immune system function by “throwing away” a specific… read more.

ACC 2014 Report: Underweight same high risk of dying as obese people

Written by | 29 Apr 2014

The connection between being underweight and the higher risk of dying is true for both adults and foetuses.  Being underweight puts people at highest risk of dying, just… read more.

ACC 2014 Report: Gastric surgery halves risk of heart attack in obese people

Written by | 24 Apr 2014

Obese people who have stomach surgery to help them lose weight will halve their risk of heart attack according to new research from a team of doctors at… read more.

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