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AstraZeneca + Saint Luke’s Mid America Heart Institute initiate phase III DARE-19 trial with Farxiga in COVID-19 patients.

Written by | 24 Apr 2020

AstraZeneca and Saint Luke’s Mid America Heart Institute have initiated a randomised, global Phase III trial to assess the potential of Farxiga (dapagliflozin) as a treatment in patients… read more.

Lynparza demonstrated overall survival benefit in phase III PROfound trial for BRCA1/2 or ATM-mutated metastatic castration-resistant prostate cancer .- AstraZeneca + Merck Inc.

Written by | 24 Apr 2020

AstraZeneca and MSD Inc., announced further positive results from the Phase III PROfound trial of Lynparza (olaparib) in men with metastatic castration-resistant prostate cancer (mCRPC) who have a… read more.

The Population Health Research Institute (PHRI) + Bayer Canada Inc. announced plans to launch a major clinical research program aimed at identifying potential COVID-19 treatments.

Written by | 24 Apr 2020

The Population Health Research Institute (PHRI) and Bayer Canada Inc. announced plans to immediately launch a major clinical research program aimed at identifying potential COVID-19 treatments. The two… read more.

Lynparza demonstrated overall survival benefit in phase III PROfound trial for BRCA1/2 or ATM-mutated metastatic castration-resistant prostate cancer .- AstraZeneca + Merck Inc.

Written by | 24 Apr 2020

AstraZeneca and MSD Inc., announced further positive results from the Phase III PROfound trial of Lynparza (olaparib) in men with metastatic castration-resistant prostate cancer (mCRPC) who have a… read more.

Positive results from phase III SPIRIT 2 study of once-daily relugolix combination therapy in women with endometriosis and from ovulation inhibition study.- Myovant Sciences

Written by | 23 Apr 2020

Myovant Sciences announced that SPIRIT 2, the first of two Phase III studies of once-daily relugolix combination therapy (relugolix 40 mg plus estradiol 1.0 mg, and norethindrone acetate… read more.

Sanofi brain-penetrant BTK inhibitor SAR 442168 significantly reduced disease activity in Phase IIb trial in relapsing multiple sclerosis.-

Written by | 23 Apr 2020

Sanofi’s investigational BTK (Bruton’s tyrosine kinase) inhibitor, an oral, brain-penetrant, selective small molecule achieved both the primary and secondary endpoints in a Phase IIb trial evaluating efficacy and… read more.

EASE study of AP 101 update of patient enrollment in Phase III trial for epidermolysis bullosa..-Amryt Pharma

Written by | 23 Apr 2020

EASE Trial of AP 101 from Amryt Pharma Update: In recent weeks, the COVID-19 pandemic has had a material impact on clinical trials globally, including patient recruitment. Given… read more.

Update on AP 101 trial as a potential treatment for epidermolysis bullosa.- Amryt

Written by | 23 Apr 2020

Amryt announced the results of an unblinded interim efficacy analysis on its pivotal Phase III EASE trial for AP 101 as a potential treatment for Epidermolysis Bullosa (“EB”).The… read more.

FDA gives Emergency Use Authorisation for Allplex 2019-nCoV Assay, a Real-time RT-PCR test for SARS-CoV-2.- Seegene

Written by | 23 Apr 2020

Seegene, Inc. announced that U.S. Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA) for its Allplex 2019-nCoV Assay, a Real-time RT-PCR test for SARS-CoV-2, the novel… read more.

Myovant Sciences submits NDA to the FDA for once-daily, oral relugolix for the treatment of men with advanced prostate cancer.

Written by | 22 Apr 2020

Myovant Sciences announced that it has submitted a New Drug Application (NDA) to the FDA for once-daily, oral relugolix (120 mg) for the treatment of men with advanced… read more.

KALM-2 pivotal phase III trial of Korsuva shows efficacy in chronic kidney disease-associated pruritus.- Cara Therapeutics/Vifor Fresenius

Written by | 22 Apr 2020

Cara Therapeutics and Vifor Fresenius Medical Care Renal Pharma announced positive topline data from Cara’s KALM-2 pivotal Phase III trial of Korsuva (CR845/difelikefalin) Injection in hemodialysis patients with… read more.

Opdivo + Yervoy improved overall survival in CHECKMATE -743 trial for patients with malignant pleural mesothelioma.-BMS

Written by | 21 Apr 2020

Bristol-Myers Squibb announced that CheckMate -743, a pivotal Phase III trial evaluating Opdivo (nivolumab) in combination with Yervoy (ipilimumab) in previously untreated malignant pleural mesothelioma (MPM) met its… read more.

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