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Regulatory applications for vericiguat to treat symptomatic chronic heart failure are filed in the EU and Japan.- Bayer HealthCare + Merck Inc.

Written by | 9 Jun 2020

Bayer announced the submission of two regulatory applications seeking the approval of vericiguat in the EU and Japan. Vericiguat is an investigational oral, once-daily, first-in-class soluble guanylate cyclase… read more.

CE Mark for OPTI SARS-CoV-2 RT-PCR laboratory test kit for the detection of SARS-CoV-2,.- Opti Medical Systems

Written by | 9 Jun 2020

OPTI Medical Systems, Inc., a subsidiary of IDEXX Laboratories, Inc. announced that it has received the CE mark certification in the European Union for its OPTI SARS-CoV-2 RT-PCR… read more.

ALN GO1 filed with EMA and FDA for primary hyperoxaluria type 1.- Alnylam Pharma

Written by | 8 Jun 2020

Alnylam Pharmaceuticals announced positive Phase III results from the ILLUMINATE-A study of ALN GO1 (lumasiran), an investigational RNAi therapeutic targeting hydroxyacid oxidase 1 (HAO1) – the gene encoding… read more.

Calquence showed promising clinical improvement in majority of 19 hospitalised COVID-19 patients .- AstraZeneca

Written by | 7 Jun 2020

Results published in Science Immunology showed that Calquence (acalabrutinib), a Bruton’s tyrosine kinase (BTK) inhibitor, reduced markers of inflammation and improved clinical outcomes of patients with severe COVID-19… read more.

New analyses of phase II EQUATOR clinical program support durable efficacy of filgotinib in psoriatic arthritis.- Gilead Sciences, Inc. + Galapagos NV

Written by | 7 Jun 2020

Gilead Sciences, Inc. and Galapagos NV announced new analyses from two clinical trials evaluating filgotinib, an investigational, oral, selective JAK1 inhibitor, in adults with psoriatic arthritis (PsA). The… read more.

Phase III APeX-2 and APeX-S trials of BCX 7353 show improvements in hereditary angioedema.- BioCryst Pharma

Written by | 7 Jun 2020

BioCryst Pharmaceuticals announced new data from the phase III APeX-2 and APeX-S clinical trials, which showed that hereditary angioedema (HAE) patients taking oral, once-daily BCX 7353 (berotralstat) experienced… read more.

Phase III SELECT-CHOICE trial of Rinvoq meets primary endpoint in rheumatoid arthritis.- AbbVie

Written by | 7 Jun 2020

AbbVie announced new Phase III data from the SELECT-CHOICE clinical trial in adult patients with moderate to severe active rheumatoid arthritis and prior inadequate response or intolerance to… read more.

Interim data from phase III HELP OLE study of Takhzyro shows efficacy in hereditary angioedema.- Takeda

Written by | 7 Jun 2020

Takeda Pharmaceutical announced findings from two new interim analyses of data from the Phase III HELP (Hereditary Angioedema Long-term Prophylaxis) Study Open-label Extension (OLE), suggesting Takhzyro (lanadelumab) is… read more.

RECOVERY trial shows no benefit from hydroxycholoroquine as treatmant for COVID-19.- Novartis

Written by | 7 Jun 2020

In March 2020 RECOVERY was established as a randomised clinical trial to test a range of potential drugs for COVID-19, including hydroxycholoroquine The trial has proceeded at unprecedented… read more.

Novartis phase IIIb ARGON study meets primary endpoint in a comparison of Enerzair Breezhaler (QVM149) versus a free combination of two existing inhaled treatments in uncontrolled asthma.

Written by | 6 Jun 2020

Novartis announced that full results from the Phase IIIb ARGON study were published online in Respiratory Medicine .. These results show that once-daily treatment with single inhaler, high-… read more.

Novartis phase IIIb ARGON study meets primary endpoint in a comparison of Enerzair Breezhaler (QVM149) versus a free combination of two existing inhaled treatments in uncontrolled asthma.

Written by | 6 Jun 2020

Novartis announced that full results from the Phase IIIb ARGON study were published online in Respiratory Medicine .. These results show that once-daily treatment with single inhaler, high-… read more.

Novartis phase IIIb ARGON study meets primary endpoint in a comparison of Enerzair Breezhaler (QVM149) versus a free combination of two existing inhaled treatments in uncontrolled asthma.

Written by | 6 Jun 2020

Novartis announced that full results from the Phase IIIb ARGON study were published online in Respiratory Medicine .. These results show that once-daily treatment with single inhaler, high-… read more.

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