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FDA approves Adcetris (brentuximab vedotin) combination regimen for the treatment of relapsed/refractory diffuse large B-cell lymphoma – Pfizer

Written by | 11 Aug 2025

Pfizer Inc. announced  that the FDA has approved the supplemental Biologics License Application (sBLA) for Adcetris (brentuximab vedotin) in combination with lenalidomide and a rituximab product for the… read more.

FDA approves Calquence (acalabrutinib) plus chemoimmunotherapy for patients with previously untreated mantle cell lymphoma – AstraZeneca

Written by | 10 Aug 2025

AstraZeneca’s Calquence (acalabrutinib) in combination with bendamustine and rituximab has been approved in the US for the treatment of adult patients with previously untreated mantle cell lymphoma (MCL)… read more.

CHMP recommends EU approval of Columvi combination for people with relapsed or refractory diffuse large B-cell lymphoma – Roche

Written by | 8 Aug 2025

Roche announced that the EMA’s Committee for Medicinal Products for Human Use (CHMP) has recommended the approval of Columvi (glofitamab) in combination with gemcitabine and oxaliplatin (GemOx) for… read more.

Understanding what makes some bladder cancers resistant to chemotherapy

Written by | 5 Aug 2025

About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To better understand why some tumors… read more.

Imfinzi-based perioperative regimen approved in the EU for resectable non-small cell lung cancer – AstraZeneca

Written by | 1 Aug 2025

AstraZeneca’s Imfinzi (durvalumab) in combination with chemotherapy has been approved in the European Union (EU) for the treatment of adults with resectable non-small cell lung cancer (NSCLC) at… read more.

Low dose olanzapine cuts chemo-induced nausea without causing sedation

Written by | 31 Jul 2025

Low-dose (5mg) olanzapine reduces chemo-induced nausea in breast cancer patients without causing sedation, researchers reported on July 1, 2025 in The Lancet Oncology. As background for this study,… read more.

FDA approves Lumakras (sotorasib) in combination with Vectibix (panitumumab) for chemorefractory KRAS G12C- mutated metastatic colorectal cancer – Amgen

Written by | 31 Jul 2025

Amgen announced that the FDA has approved Lumakras (sotorasib) in combination with Vectibix (panitumumab) for the treatment of adult patients with KRAS G12C-mutated metastatic colorectal cancer (mCRC), as… read more.

ESMO 2025: Moderna presents mRNA immunotherapy advances in melanoma and NMIBC

Written by | 29 Jul 2025

Moderna, Inc. announced that three abstracts on its investigational mRNA therapeutics have been accepted for presentation at the 2025 European Society for Medical Oncology (ESMO) Congress, which will… read more.

Enhertu (trastuzumab deruxtecan) supplemental New Drug Application submitted in Japan for patients with HER2 positive metastatic solid tumors – Daiichi Sankyo

Written by | 27 Jul 2025

Daiichi Sankyo  has submitted a supplemental New Drug  Application (sNDA) to Japan’s Ministry of Health, Labour and Welfare (MHLW) for Enhertu (trastuzumab deruxtecan) for the treatment of adult… read more.

Incyte to present early data on KRAS G12D and PD-1/TGFβR2 candidates at ESMO 2025

Written by | 26 Jul 2025

Incyte announced that the Company will present key data from its oncology portfolio at the upcoming European Society of Medical Oncology (ESMO) Congress 2025, to be held October 17-21 in Berlin. “We’re looking… read more.

Tecartus demonstrates high response rate in adults with relapsed or refractory B-cell acute lymphoblastic leukemia – Kite/Gilead

Written by | 23 Jul 2025

Kite, a Gilead Company announced results from the primary analysis of ZUMA-3, a global, multicenter, single-arm, open-label Phase 1/II study evaluating its chimeric antigen receptor (CAR) T-cell therapy… read more.

NICE (UK) terminated appraisal for Tevimbra (tislelizumab) in combination for untreated advanced non-small-cell lung cancer – BeiGene

Written by | 22 Jul 2025

NICE is unable to make a recommendation on tislelizumab (Tevimbra) in combination for untreated advanced non-small-cell lung cancer in adults. This is because the company did not provide… read more.

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