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Drug discovery offers potential treatment for common kidney disease

Written by | 17 Dec 2022

A serious condition that can cause the kidneys to suddenly stop working could be treated with existing medicines, a new study shows. In a study in mice scientists… read more.

Early diagnosis tool for childhood kidney disease

Written by | 13 Nov 2022

Early diagnosis of chronic kidney disease (CKD) is key to managing progression of the disease. A new technique analyzing urine extracellular vesicles (uEVs) — cell-derived nanoscale spherical structures… read more.

Widely-used kidney function tests underestimate scale of kidney disease

Written by | 15 Jul 2022

The findings suggest that methods developed in high-income settings to check kidney function are not accurate for many people in Africa. Researchers from the African Research on Kidney… read more.

Genetic screening algorithm could identify people with kidney disease risk

Written by | 21 Jun 2022

A new algorithm developed by researchers at Columbia University can analyze thousands of variants across the genome and estimate a person’s risk of developing chronic kidney disease —… read more.

EMA accepts marketing authorisation application for daprodustat to treat anaemia of chronic kidney disease – GSK

Written by | 26 Apr 2022

GlaxoSmithKline plc announced that the European Medicines Agency (EMA) validated the marketing authorisation application (MAA) for daprodustat, an investigational oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), for the… read more.

Study shows dramatic long-term complications in youth-onset type 2 diabetes

Written by | 27 Aug 2021

Researchers report that patients diagnosed with type 2 diabetes in their youth are, by young adulthood, at risk of serious complications. The findings from the TODAY2 study (Treatment… read more.

FibroGen receives Complete Response Letter from the FDA for roxadustat for anemia of chronic kidney disease – FibroGen + AstraZeneca

Written by | 22 Aug 2021

The FDA has issued a complete response letter (CRL) regarding the New Drug Application (NDA) for roxadustat for the treatment of anaemia of chronic kidney disease (CKD), in… read more.

GSK announces positive headline results from five phase III studies of daprodustat for patients with anaemia due to chronic kidney disease

Written by | 28 Jul 2021

GlaxoSmithKline plc announced positive headline results from five studies of the Phase III ASCEND programme, evaluating the efficacy and safety profile of daprodustat, an investigational oral hypoxia-inducible factor… read more.

FDA approves Kerendia in chronic kidney disease (CKD) associated with type 2 diabetes – Bayer HealthCare

Written by | 21 Jul 2021

Bayer announced the FDA has approved Kerendia (finerenone), a first-in-class nonsteroidal mineralocorticoid receptor antagonist (MRA) indicated to reduce the risk of sustained eGFR decline, kidney failure, cardiovascular death,… read more.

Advicenne receives MHRA approval to market Sibnayal in the UK for the treatment of distal renal tubular acidosis

Written by | 14 Jul 2021

Advicenne announces that the Medicines & Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation for Sibnayal (ADV 7103) in the UK, for the treatment of distal renal… read more.

Researchers find enzyme that could unlock kidney treatment

Written by | 15 May 2021

Article written by Gary Finnegan. Chronic kidney disease affects approximately 700 million people worldwide with many going on to require dialysis. Now a new enzyme has been discovered… read more.

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes – AstraZeneca

Written by | 3 May 2021

AstraZeneca’s Farxiga (dapagliflozin), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, has been approved in the US to reduce the risk of sustained estimated glomerular filtration rate (eGFR) decline, end-stage… read more.

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