Ganitumab disappoints in pancreatic cancer: Amgen halts Phase III Study
In a press release on August 8, 2012, Amgen announced that the company was halting a late-stage trial of its monoclonal antibody IGF-1 receptor antagonist ganitumab (AMG-479).
In a press release on August 8, 2012, Amgen announced that the company was halting a late-stage trial of its monoclonal antibody IGF-1 receptor antagonist ganitumab (AMG-479).
In news that is bound to excite breast cancer patients and investors, Genentech/Roche/Immunogen issued press releases on August 26, 2012, confirming that their drug-of-the-moment T-DM1 (trastuzumab emtansine) offers… read more.
The end of July 2012 proved exciting for the world of biosimilar manufacturers. However, for the regulatory officials worldwide it meant more uncertainty and unknowns about proper, global… read more.
by Thomas R. Collins – Using everolimus for immunosuppression in heart transplant recipients, along with a reduced amount of cyclosporine, produces results comparable to mycophenolate mofetil,
by Thomas R. Collins – TOL101, a new murine monoclonal antibody that targets the alpha-beta T-cell receptor, showed a good safety profile despite a problem with hives that… read more.
by Thomas R. Collins – Using a high dose of insulin is associated with a high risk of pancreas loss after a simultaneous pancreas kidney transplant, researchers said… read more.
by Thomas R. Collins – Total pancreatectomy and auto islet transplantation among children can bring about good results, with many able to stay insulin-free and almost all of… read more.
by Thomas R. Collins – The blood pressure of the kidney transplant recipient at the University of Glasgow kept climbing. But it wasn’t without effort from physicians.
by Thomas R. Collins – The functional status of transplant recipients is a factor that is often overlooked as kidneys are allocated,
by Thomas R. Collins – The BK virus, and damage to the kidney that is caused by it, poses a continuing challenge to kidney transplant specialists.
by Thomas R. Collins – Antibodies play diverse roles in the human body — they can be anti-inflammatory, they can modulate the immune system, and they can be protective… read more.
by Thomas R. Collins – A method for cross-matching organ donors and recipients — using beads and human complement — is producing more reliable results, making for transplantation of hearts… read more.