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FDA accepts for review supplemental application for Abrilada interchangeability – Pfizer

Written by | 5 Jun 2022

Pfizer Inc. announced that the FDA has accepted for review the Prior Approval Supplement (PAS) to the Biologics License Application (BLA) for Abrilada (adalimumab-afzb) as an interchangeable biosimilar… read more.

New study shows genes can predict response to arthritis treatment and paves the way for future drug development

Written by | 31 May 2022

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will… read more.

Older adults with rheumatoid arthritis still undermedicated, despite aggressive guidelines

Written by | 27 May 2022

Despite guidelines that call for early and aggressive treatment of rheumatoid arthritis, a new study suggests many older adults are not prescribed disease-modifying medications for their inflammatory autoimmune… read more.

Rheumatoid arthritis drug cuts mortality among COVID-19 ventilated patients

Written by | 19 Feb 2022

Critically ill COVID-19 patients already on mechanical ventilation or extracorporeal membrane oxygenation have achieved a significantly higher rate of survival when randomized to receive baricitinib, a treatment for… read more.

AbbVie provides update on Rinvoq for the treatment of rheumatoid arthritis in the U.S

Written by | 30 Jan 2022

AbbVie announced an update to the U.S. Prescribing Information and Medication Guide for Rinvoq (upadacitinib) for the treatment of adults with moderate to severe rheumatoid arthritis (RA). This… read more.

New EULAR consensus on prevention trials in people at risk of developing RA

Written by | 27 Oct 2021

RA is an inflammatory autoimmune disease that causes pain, swelling and stiffness in the joints. It can also cause fatigue, and the underlying inflammation may affect other body… read more.

Parental smoking may increase children’s risk of developing rheumatoid arthritis

Written by | 16 Oct 2021

New research published in Arthritis & Rheumatology links parental smoking with an elevated risk of rheumatoid arthritis in children when they reach adulthood. Among 90,923 participants in the Nurses’ Health… read more.

FDA requires warnings about increased risk of serious heart-related events, cancer, blood clots, and death for JAK inhibitors that treat certain chronic inflammatory conditions

Written by | 10 Sep 2021

Based on a completed FDA review of a large randomized safety clinical trial, the FDA has concluded there is an increased risk of serious heart-related events such as… read more.

CD14+ monocytes and RA – implications for practice and research

Written by | 19 Mar 2021

Interview and article by Christine Clark. Dr Megan Hanlon and Professor Ursula Fearon describe the implications of their research findings for future practice and research in rheumatoid arthritis…. read more.

Investigating the inflammatory changes of RA at molecular level

Written by | 18 Mar 2021

Interview and article by Christine Clark. Professor Ursula Fearon and Dr Megan Hanlon describe a study that investigated the metabolic behaviour of circulating monocytes and how this relates… read more.

The pathological development of rheumatoid arthritis

Written by | 17 Mar 2021

Interview and article by Christine Clark. Recent research into the molecular basis for rheumatoid arthritis may be pointing the way to targeted therapy to prevent inflammation and joint… read more.

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