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NICE (UK) positive update for Filspari (sparsentan) for treating primary IgA nephropathy – CSL Vifor

Written by | 17 Nov 2025

NICE (UK): Sparsentan can be used as option to treat primary immunoglobulin A nephropathy (IgAN) in adults with a: i) urine protein-to-creatinine ratio (UPCR) of 85 mg/mmol or… read more.

Fabhalta (iptacopan) meets Phase III primary endpoint, slows kidney function decline in patients with IgA nephropathy – Novartis

Written by | 22 Oct 2025

Novartis announced positive final results from APPLAUSE-IgAN, a Phase III study evaluating Fabhalta (iptacopan) in adults living with IgA nephropathy (IgAN). Fabhalta, an oral alternative complement pathway inhibitor,… read more.

FDA accelerated approval for Fabhalta (iptacopan), the first and only complement inhibitor for the reduction of proteinuria in primary IgA nephropathy – Novartis

Written by | 14 Aug 2024

Novartis announced that the FDA has granted accelerated approval for Fabhalta (iptacopan), a first-in-class complement inhibitor for the reduction of proteinuria in adults with primary immunoglobulin A nephropathy… read more.

Nefecon filed with EMA for primary IgA Nephropathy – Calliditas Therapeutics

Written by | 7 Jun 2021

Calliditas Therapeutics has submitted a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for Nefecon (budesonide), a novel oral formulation targeting down regulation of IgA1 for… read more.

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