AASLD 2024: Mirum presents breakthrough data on Maralixibat and Volixibat for cholestatic liver diseases

Mirum Pharmaceuticals, Inc. (announced that it will present data at the American Association for the Study of Liver Disease’s (AASLD) The Liver Meeting®, taking place November 15-19, 2024, in San Diego, California.

Enclosed below are the titles that have been accepted for presentation during the meeting. The abstracts are available via the AASLD website. Full analyses will be available following their presentation within the Publications & Presentation section on Mirum’s website.

 

Presentations

 

Abstract #5038: Volixibat for Cholestatic Pruritus in Primary Biliary Cholangitis: An Adaptive, Randomized, Placebo-controlled Phase 2b Trial (VANTAGE): Interim Results
**Late-breaker poster presentation**
Monday, November 18 from 1:00-2:00pm, Poster Hall C
Presented by Dr. Kris Kowdley, Washington State University, Seattle, Washington, USA

 

Abstract #184: Improvements in Pruritus are Associated with Improvements in Growth in Patients with Progressive Familial Intrahepatic Cholestasis: Data from the MARCH-ON trial
**Oral presentation**
Sunday, November 17 from 12:15-12:30pm during the ‘Advances in Pediatric Liver Disease’ session, Ballroom 6C
Presented by Dr. Alexander Miethke, Cincinnati Children’s Hospital, Cincinnati, Ohio, USA

 

Abstract #4347: Pilot Study of Volixibat Co-administered with OCA for Primary Biliary Cholangitis (PBC) Treatment: The VLX-602 Trial
Monday, November 18 from 1:00-2:00pm during Poster Session IV, Poster Hall C
Presented by Dr. Kris Kowdley, Washington State University, Seattle, Washington, USA

 

Abstract #4400: Impact of Maralixibat on Caregiver Burden for Patients with Alagille Syndrome and Progressive Familial Intrahepatic Cholestasis
Monday, November 18 from 1:00-2:00pm during Poster Session IV, Poster Hall C
Presented by Dr. Natasha Dilwali, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

 

Abstract #4419 : Real-world Use of Maralixibat in Biliary Atresia: A Case Series
Monday, November 18 from 1:00-2:00pm during Poster Session IV, Poster Hall C
Presented by Dr. Natasha Dilwali, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

 

Abstract #4432: The Relationship Between Serum Bile Acids and Event-Free Survival Following the Use of Maralixibat for Progressive Familial Intrahepatic Cholestasis: Data from MARCH/MARCH-ON
Monday, November 18 from 1:00-2:00pm during Poster Session IV, Poster Hall C
Presented by Professor Richard Thompson, King’s College London, United Kingdom

 

Abstract #4436: Bile Acid Subspecies are Correlated with Pruritus and Bilirubin Improvement in PFIC Patients Treated with Maralixibat: Data from MARCH and MARCH-ON
Monday, November 18 from 1:00-2:00pm during Poster Session IV, Poster Hall C
Presented by Professor Henkjan Verkade, University of Groningen, Groningen, Netherlands