BridgeBio to present new data on Acoramidis and ATTR-CM outcomes at Heart Failure 2025

BridgeBio Pharma, Inc. a new type of biopharmaceutical company focused on genetic diseases, announced that one rapid-fire abstract and two moderated ePosters on the clinical outcomes and quality of life measures provided by acoramidis in variant transthyretin amyloid cardiomyopathy (ATTR-CM) and one moderated ePoster on a post-hoc analysis of the lower incidence rate of atrial fibrillation-related events in patients with ATTR-CM, all from the ATTRibute-CM study will be shared at the Annual Congress of the Heart Failure Association of the ESC (Heart Failure 2025), taking place in Belgrade, Serbia on May 17 – 20, 2025.

In addition to the four abstracts, three moderated ePosters will be shared on the disease progression of ATTR-CM in a real-world setting, a retrospective cohort study on manifestation to diagnosis of ATTR-CM, and data on the cause of death of ATTR-CM patients in the ATTRibute-CM study.

Rapid-fire Abstract

Acoramidis Improves Serum TTR Levels in Patients with Wild-type or Variant Transthyretin Amyloid Cardiomyopathy: Results from ATTRibute-CM
Presenter: Anique Ducharme, M.D., Université de Montréal, CAN
Date: Tuesday, May 20 at 8:30 am CEST/2:30 am ET

Moderated ePosters:

Effect of Acoramidis on Functional Capacity and Quality of Life in Patients with Variant ATTR-CM: Results from ATTRibute-CM
Presenter: Marianna Fontana, M.D., University College London, UK
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET

Effect of Acoramidis on All-cause Mortality, Cardiovascular Hospitalization and NT-proBNP in Variant ATTR-CM: Results from ATTRibute-CM
Presenter: Marianna Fontana, M.D., University College London, UK
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET

Acoramidis Treatment Is Associated with a Lower Incidence of Atrial Fibrillation-related Events in Patients with ATTR-CM: A Post Hoc Analysis of the ATTRibute-CM trial
Presenter: Kevin Alexander, M.D., Stanford University School of Medicine, USA
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET

Disease Progression Among Patients Receiving Tafamidis for ATTR-CM in a Real-world Setting
Presenter: Daniel P. Judge, M.D., Medical University of South Carolina, USA
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET

Cause of Death in Patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM): Findings from the ATTRibute-CM study
Presenter: Laura Obici, M.D., University of Pavia, ESP
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET

Time from First Recorded Clinical Manifestation to Diagnosis of Transthyretin Amyloid Cardiomyopathy: A Retrospective Cohort Study Using U.S. Claims Data
Presenter: Joshua Mitchell, M.D., Washington University School of Medicine in St. Louis, USA
Date: Sunday, May 18 at 11:00 am CEST/5:00 am ET